Humans (Homo sapiens) are highly intelligent primates that have become the dominant species on Earth.
Serotonin receptors are activated by the neurotransmitter like serotonin, which acts as their natural ligand. Other endogenous small molecules, like N-dimethyltryptamine (DMT) and Lysergic acid diethylamide (LSD), competitively bind Serotonin Receptors producing transcendental psychedelic effects. (more…)
Caffeine is a weak, non-selective antagonist of adenosine receptors. This 3D print of Adenosine Receptor (tinted brown) in Complex with Caffeine (colored by atom type) is designed to visualize the location Caffeine (color by atom type) binds to the receptor-binding pocket. (more…)
Cannabinoid receptors are part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory. This 3D print of THC Cannabinoid Receptor Complex 5TGZ is designed to visualize THC (color by atom type) bound inside the receptor-binding pocket. (more…)
A nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones. (more…)
Interleukin 8 (IL8 or chemokine ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells, and endothelial cells. (more…)
T-cell receptors (TCR) are a protein complex found on the surface of T cells that are responsible for identifying fragments of antigen bound to major histocompatibility complex (MHC) molecules. (more…)
High-density lipoprotein (HDL), the carrier of so-called “good” cholesterol, serves as the major athero-protective lipoprotein and has emerged as a key therapeutic target for cardiovascular disease. (more…)
Human cytomegalovirus (HCMV) poses a significant threat to immunocompromised individuals and neonates infected in utero. Glycoprotein B (gB), the herpesvirus fusion protein, is a target for neutralizing antibodies and a vaccine candidate due to its indispensable role in infection. HCMV is the leading infectious cause of congenital abnormalities in the Wwestern world (more…)
Cannabinoid receptors are part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory. This 3D print of THC Cannabinoid Receptor Complex 5TGZ is designed to visualize THC bound inside the receptor-binding pocket. (more…)
A Nucleosome is the basic structural unit of DNA that assembles into a chromosome. Each nucleosome consists of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool. Use this 3D printed model Nucleosome 3C1B showing how DNA wraps around a histone core to explain…
Glycated Hemoglobin HbA1c Elevated blood sugar attaches to hemoglobin Hb, the protein inside red blood cells. Use a 3D printed protein model of Glycated Hemoglobin HbA1c to explain the HbA1c diabetes blood test. (more…)
Human Insulin Hexamer Use this 3D printed Biologic Model of Human Insulin Hexamer as a desktop reminder to take your medication before each meal. (more…)
Psilocybin bound to Serotonin Receptor Psilocybin, the active ingredient in psychoactive mushrooms, has provided the spiritual and cultural bedrock of many great civilizations. The Aztecs referred to teonanácatl, which translates as ‘divine mushroom’, and modern neuroscience has revealed how psilocybin interacts with serotonin receptors in the brain in order to produce a range of consciousness-altering…
Nucleosome 1KX5 A nucleosome is a basic unit of DNA, consisting of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool. (more…)
TDP-43 Wild Type and Mutant in Complex with DNA ALS is a fatal motor neuron disorder characterized pathologically by TAR DNA binding protein ( TDP-43 ). The function of TDP-43 is uncertain, and role in ALS remains speculative. Genome scanning reveals mutations associated to neural apoptosis. (more…)
EGFR Mutant Tyrosine Kinase Mutations in EGFR lead to over-expression of proteins and different types of cancers as cells continually and proliferate. This 3D print of EGFR Tyrosine Kinase visualizes the mutations of key residues that lock the protein’s A-loop (orange) in its active conformation resulting in continued cellular proliferation. (more…)
EGFR Wild Type Tyrosine Kinase This is a 3D print of X-ray crystallography dataset 4HJO, the Crystal Structure of the Inactive EGFR Tyrosine Kinase Domain with Erlotinib. (more…)
Monoclonal IgG4 Antibody bound to PD1 Humanized antibody are used in cancer immunotherapy to target the programmed cell death receptor (PD-1). Without the PD-1 protective mechanism, the antibody allows the immune system to destroy cancer cells. Explore the 3D structure with our interactive 3D models. (more…)
Oxygenated Hemoglobin Hb Hemoglobin, the protein from inside red blood cells, transports oxygen molecules throughout the body. Its macro-molecular symmetrical structure just the first interesting characteristic of this fascinating molecule. Explore its 3D structure with our 3D printed protein models of Oxygenated Hemoglobin Hb. (more…)
Muscarinic Acetylcholine Receptor 3UON Muscarinic acetylcholine receptors are G protein-coupled receptor complexes in the cell membranes of certain neurons and cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. This 3D printed protein model of muscarinic acetylcholine receptor is visualized by its ribbon structure highlighting the protein’s transmembrane active sites. (more…)
