This is a 3D print of human insulin in its stable macro-molecule hexamer form. It is colored by the protein’s bFactor or atomic temperature. Chains A and C are stained yellow, and Chains B and D are stained lite orange. The core of the macromolecule shows the stable, cool binding region of each monomer, an important […]
CRISPR Cas9 printed in full-color sandstone colored purple according to the protein’s bFactor, it’s propensity for movement. RNA is colored red, DNA colored Yellow and Green. Protein Description “The RNA-guided DNA endonuclease CRISPR Cas9 cleaves double-stranded DNA targets with a protospacer adjacent motif (PAM) and complementarity to the guide RNA. Recently, we harnessed Staphylococcus aureus […]
3D print of Pembrolizumab (KEYTRUDA) bound to PD-1. Model available in multiple materials and sizes. “Pembrolizumab (formerly MK-3475and lambrolizumab, trade name Keytruda) is a humanized antibodyused in cancer immunotherapy. It destroys a protective mechanism on cancer cells, and allows the immune system to destroy those cancer cells. It targets the programmed cell death 1(PD-1) receptor. The drug was initially used in treating metastatic melanoma.” Protein […]
Model Description 3D print of T4 Phage bound to single stranded DNA. Multiple materials and sizes available. (more…)
Happy Holidays from Biologic Discovery! 3D Print of a CENP-A-histone H4 complex bound to the Holiday Junction. (more…)
This is a photo from a recent conference where our models were used to explain how different companies are using CRISPR in agriculture. Explore CRISPR Find out more about CRISPR by exploring different CRISPR projects we’ve created.
Download the free CRISPR Cpf1 Augmented Reality App and explore the protein’s internal atomic structure. Launch the Biologic Explorer and point your phone at this QR Code to launch a digital model of CRISPR Cpf1. Toggle on and off different structures to reveal the hidden beauty of x-ray crystallography data. Download the CRISPR Cpf1 Augmented Reality […]
This is an Interactive Model of Glycated Hemoglobin A1c. It is a made from high-quality plastics cast from silicon molds. Attached the transparent surface of Hemoglobin are 16 magnetized pieces of glucose. Each piece is held in place by a magnet cast inside the plastic model. I designed this model to help explain the complex […]
This 3D print of Niemann-Pick C1 is printed in full-color sandstone and colored by the protein’s hydrophobicity. Blue is are the hydrophilic regions of the protein, and red colors the hydrophobic regions. Since this is a membrane bound protein, visualizing its hydrophobicity allows us to visually identify the hydrophobic portion that spans the plasma membrane. Models are […]
Immunotherapy is the treatment of cancer using antibodies that target points of failure in the life cycle of cancer cells. Many of these therapies involve altering monoclonal antibodies to target specific proteins associated with different types of cancer. Understanding the binding properties of these proteins is of utmost importance. Pembrolizumab, an igG4 Monoclonal Antibody Some […]
3D Print of Phosphoinositide 3-Kinase (PI3K) denoting common mutation sites (E545, H1047) that result in an oncogenic enzyme. This model was created from PDB dataset: 5DXT and visualizes the PI3K inhibitor GDC-0326. Protein Description PI3K are a family of enzymes involved in cellular functions such as cell growth, proliferation, differentiation, motility, survival and intracellular trafficking, which in turn are involved in […]
This is a 3D print of PARP1 bound by Zejula, the first in class drug for women with recurrent ovarian cancer, regardless of BRCA mutation. Zejula is an oral medication taken once daily. Protein Description Poly(ADP-ribose) polymerase 1 (PARP1) is an enzyme that in humans is encoded by the PARP1 gene. It is one of the PARP family of enzymes. […]
Trial Room Exhibits Occasionally, attorneys will contact me and request media to be used in trials or witness depositions. Attorneys understand that medical procedures and personal injuries are difficult to explain verbally. Testimony relies on verbal explanations of things that require knowledge that most jurors simply don’t have. They often request 3D animations to simplify how trauma […]
Hemoglobin A1c Blood Test The Hemoglobin A1c (HbA1c) blood test is given to nearly every single person living with diabetes and anyone at risk of developing diabetes. It is the preferred diagnostic tool used around the world to measure a patient’s long-term self-management of diabetes. Hundreds of millions of people each year will receive this test. Yet, despite […]
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