PIP4K II Alpha and Beta
Recently, Cornell University commissioned us to create 3D printed models of PIP4K II Alpha and Beta for the purpose of demonstrating PIP4K dimerization.
RSV Fusion Glycoprotein
The Human Respiratory Syncytical Virus (HSV) is a major cause of lower respiratory track infection. Deadly to newborn babies, new thereapies are being developed to keep infants alive. The Fusion Glycoprotein is the key mechanism of viral infection, binding to lung cells exhibiting a dynamic conformational change. This Biologic Model series explorers the conformation state changes of this "harpoon-like" protein using both 3D printed protein models and digital real-time 3D interactives.
Glycated Hemoglobin HbA1c3D reproduction of Glycated Hemoglobin HbA1c protein. Glucose and fructose attach to hemoglobin in a process called glycosylation. When sugar attaches to proteins, it changes the protein's shape, impairing its ability to achieve its maximum conformation state and function.
This is a 3D print of Shiga Toxin (Stk1) created from protein dataset 1DM0 This model is colored by protein chain. The 5 blue chains are the membrane binding domains and the red the cytotoxic compounds.
This 3D printed protein model of Asparaginase identifies an engineered mutation that extends the protein's half-life. It is printed in full-color sandstone color green to blue by the protein's bFactor. In red is the site of the mutation responsible for prolonging the protein's half-life.
This 3D print of MT-3724 demonstrates a unique mechanism of action of this immunotoxin. MT-3724 is a new type of immunotherapy developed by Molecular Templates.
ETH Zurich researchers make a major breakthrough in our understanding of the glycosylation process after crystallization of the Oligosaccharyltransferase (OST) Complex, the protein that attaches sugar chains. Biologic Models visualizes this dataset as a 3D Printed Protein Model.
Zika Virus Shell
This is a 3D print of the Zika Virus with a digital QRC code base. Green colored proteins chains and yellow active sites demonstrate the complexity and beauty of this dangerous virus. Prints available in multiple sizes (small, medium, and large) through our shapeways.com store. Purchase through the Biologic Models shop and take an extra 10% the medium size molecular model kit.
CRISPR Cas9 Bound to Guide RNA and Target DNA
This is a 3D print of CRISPR Ca9 is created in full-color sandstone. The model depicts CRISPR (purple) bound to its guide RNA (red) while editing its Target DNA (yellow and green). The subtle color variations in the CRISPR are associated with its bFactor, or atomic temperature. The darker the color, the less the protein moves with a cooler atomic temperature.
CRISPR Cpf1 Bound to Guide RNA and Target DNA
From x-ray crystallography data to 3D printed model to augmented reality app, this CRISPR Cpf1 protein guide explains the inner workings of this amazing genome editing system.