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EGFR Mutant Tyrosine Kinase

EGFR, Mutant, Biologic Models

EGFR Mutant Tyrosine Kinase Mutations in EGFR lead to over-expression of proteins and different types of cancers as cells continually and proliferate. This 3D print of EGFR Tyrosine Kinase visualizes the mutations of key residues that lock the protein’s A-loop (orange) in its active conformation resulting in continued cellular proliferation. (more…)

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Monoclonal IgG4 Antibody bound to PD1

Pembrolizumab, ( KEYTRUDA ), PD1, Keytruda, Biologic Models

Monoclonal IgG4 Antibody bound to PD1 Humanized antibody are used in cancer immunotherapy to target the programmed cell death receptor (PD-1). Without the PD-1 protective mechanism, the antibody allows the immune system to destroy cancer cells. Explore the 3D structure with our interactive 3D models. (more…)

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