Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body.
EGFR Mutant Tyrosine Kinase Mutations in EGFR lead to over-expression of proteins and different types of cancers as cells continually and proliferate. This 3D print of EGFR Tyrosine Kinase visualizes the mutations of key residues that lock the protein’s A-loop (orange) in its active conformation resulting in continued cellular proliferation. (more…)
EGFR Wild Type Tyrosine Kinase This is a 3D print of X-ray crystallography dataset 4HJO, the Crystal Structure of the Inactive EGFR Tyrosine Kinase Domain with Erlotinib. (more…)
Monoclonal IgG4 Antibody bound to PD1 Humanized antibody are used in cancer immunotherapy to target the programmed cell death receptor (PD-1). Without the PD-1 protective mechanism, the antibody allows the immune system to destroy cancer cells. Explore the 3D structure with our interactive 3D models. (more…)
Apaf-1 Caspase-9 Holoenzyme This is a 3D print of Apaf-1 activating Caspase-9, a key protein involved in apoptosis, or programmed cell death. This model is colored by individual protein chains, with Caspace-9 colored shades of blue and Apaf-1 colored shades of magenta. (more…)
Sphingosine kinase This is a 3D print of Sphingosine Kinase, colored by the protein’s bFactor, or atomic temperature (blue cool, red hot). The model is available in multiple sizes. (more…)
