Interleukin 8 (IL8 or chemokine ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells, and endothelial cells.
Protein Description 3IL8
The crystal structure of a host defense system chemotactic factor, interleukin 8 (IL-8), has been solved by molecular replacement using as a model the solution structure derived from nuclear magnetic resonance experiments. The structure was refined with 2 A x-ray data to an R factor of 0.187 (0.217 at 1.6 A). A comparison indicates some potential differences between the structure in solution and in the crystalline state. Our analysis also predicts that residues 4 through 9 on the amino terminus and the beta-bend, which includes His-33, may be important for receptor binding.
Biologic Explorer 3IL8
Model Description
Biologic Model of Interleukin 8 created from PDB ID: 3IL8 3D printed in Multi-colored Plastic.
