Structural and Functional proteins of different viruses.
Poliovirus Type 2 This is 3D protein model of the Poliovirus Type 2 3D printed in full-color sandstone or plastic and colored to denote the locations of active residues targeted by antibodies. Despite the Type 2 wild poliovirus being declared eradicated in September 2015, a vaccine-derived mutated version of the vaccine-virus has reemerged in…
The severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) variant Omicron spread more rapid than the other variants of SARS-CoV-2 virus. Simulation results show that the Omicron Variant have stronger binding to ACE2 than other variants. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain Omicron Mutant 6VXX helps research…
The SARS-CoV2 Delta Plus variant was first reported in India. This new variant, was shown to carry mutation K417N on its receptor-binding domain (RBD), a mutation previously reported in the Beta variant. Experts believe it contributes to immune evasion in SARS-CoV-2 and synergistic with mutation L452R, another mutation known to also contribute to immune evasion.…
The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain (RBD) ACE2 Receptor Complex 6M17 to help research scientists and the general public better understand how SARS-CoV-2 binds ACE2 Receptors. (more…)
The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain Neutralizing Antibody Complex 7KS9 to help research scientists and the general public better understand how to neutralize Spike Glycoprotein. (more…)
The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain 6VXX to help research scientists and the general public better understand the binding properties of the Spike Glycoprotein and how it compares to other Coronavirus Spike Glycoproteins.…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The structural proteins of SARS-CoV-2 are key targets for vaccines, therapeutic antibodies, and diagnostics. The 3D printed structure of SARS-CoV-2 Virion should enable the rapid development and evaluation of medical countermeasures to address…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein 7KS9 to help scientists better visualize…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein Postfusion 6XRA to help scientists better…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. The 3D printed structure of SARS-CoV-2 Spike Glycoprotein ACE2 Complex 6VXX-6M17 is designed to enable the rapid development and…
This 3D printed protein model of SARS-CoV-2 Spike Glycoprotein 3D printed and colored-coded to denote functional domains (NTD blue, RBD green, SD1, light tan, SD2 red-orange-yellow, FP cyan, RRAR brown). (more…)
Human cytomegalovirus (HCMV) poses a significant threat to immunocompromised individuals and neonates infected in utero. Glycoprotein B (gB), the herpesvirus fusion protein, is a target for neutralizing antibodies and a vaccine candidate due to its indispensable role in infection. HCMV is the leading infectious cause of congenital abnormalities in the Western world including hearing loss.…
The SARS-CoV1 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV1 Receptor Binding Domain 5X58 to help research scientists and the general public better understand the binding properties of the Spike Glycoprotein and how it compares to other Coronavirus Spike Glycoproteins.…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 RNA Polymerase is a key target for antiviral therapy. The 3D printed structure of SARS-CoV-2 RNA Polymerase inhibited by Remdesivir should enable the rapid development and evaluation of medical countermeasures to address…
Deadly to newborn babies, the Human Respiratory Syncytial Virus (HSV) is a major cause of lower respiratory tract infection. Dynamic structural changes in the Fusion F Glycoprotein reveal and hide binding sites, making targets of new therapies difficult to identify. Explore RSV Fusion F Glycoprotein-3RRR and learn more about its Postfusion 3D structure. (more…)
The Human Cytomegalovirus (HCMV) is the leading cause of viral birth defects. HCMV Pentamer Complex is considered a key target candidate for vaccine therapies. How HCMV avoids humoral immunity is not clear. New research into the elusive virus reveals the surprising role of the host cell’s endoplasmic reticulum to aid viral infection. (more…)
Zika Virus Shell This is 3D protein model of the Zika Virus Shell 3D printed in full-color sandstone and denotes the locations of active residues targeted by antibodies. (more…)
This is a 3D print of the RSV Fusion Glycoprotein in its prefusion state. The 3D printed protein models of RSV Fusion F Glycoprotein visualize the conformational changes of this viral protein during membrane fusion. Two chains are colored shades of magenta, with the third chain colored blue to red from N to C-Terminal. (more…)
Ebolavirus (EBOV) is a highly virulent pathogen capable of causing a severe hemorrhagic fever with 50–90% lethality. The EBOV glycoprotein (GP) is the only virally expressed protein on the virion surface and is critical for attachment to host cells. 3D print model the ectodomain of the Ebolavirus. (more…)
