The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. The structure of SARS-CoV-2 Spike Glycoprotein 6VXX should enable the rapid development and evaluation of medical countermeasures to address…
Researchers at EMBL in Hamburg recently discovered that the Tuberculosis bacteria has a special toxin-antitoxin system with a surprising function. Once the system activated, all bacterial cells die and stop the disease. (more…)
A Nucleosome is the basic structural unit of DNA that assemble into a chromosome. Each nucleosome consists of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool. Use this 3D printed model of DNA wrapped around a histone core to explain how DNA is…
Deadly to newborn babies, the Human Respiratory Syncytial Virus (HSV) is a major cause of lower respiratory tract infection. Dynamic structural changes in the Fusion F Glycoprotein reveal and hide binding sites, making targets of new therapies difficult to identify. Explore RSV Fusion F Glycoprotein-3RRR and learn more about its Postfusion 3D structure. (more…)
Glycated Hemoglobin HbA1c Elevated blood sugar attaches to hemoglobin Hb, the protein inside red blood cells. Use a 3D printed protein model of Glycated Hemoglobin HbA1c to explain the HbA1c diabetes blood test. (more…)
Human Insulin Hexamer Use this 3D printed Biologic Model of Human Insulin Hexamer as a desktop reminder to take your medication before each meal. (more…)
Psilocybin bound to Serotonin Receptor Psilocybin, the active ingredient in psychoactive mushrooms, has provided the spiritual and cultural bedrock of many great civilisations. The Aztecs referred to teonanácatl, which translates as ‘divine mushroom’, and modern neuroscience has revealed how psilocybin interacts with serotonin receptors in the brain in order to produce a range of consciousness-altering effects.…
Argonaute Protein Small RNA sequences guide Argonaute Protein (Apo) to its specific DNA targets, which then leads to mRNA cleavage or translation inhibition. Inside the gut, bacteria express control over their host organism by secreting Nitric Oxide which modulates Apo function. Explore the 3D structure of Argonaute Protein. (more…)
The Human Cytomegalovirus (HCMV) is the leading cause of viral birth defects. HCMV Pentamer Complex is considered a key target candidate for vaccine therapies. How HCMV avoids humoral immunity is not clear. New research into the elusive virus reveals the surprising role of the host cell’s endoplasmic reticulum to aid viral infection. (more…)
Nucleosome 1KX5 A nucleosome is a basic unit of DNA, consisting of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool. (more…)
TDP-43 Wild Type and Mutant in Complex with DNA ALS is a fatal motor neuron disorder characterized pathologically by TAR DNA binding protein ( TDP-43 ). The function of TDP-43 is uncertain, and role in ALS remains speculative. Genome scanning reveals mutations associated to neural apoptosis. (more…)
Zika Virus Shell This is 3D protein model of the Zika Virus Shell 3D printed in full-color sandstone and denotes the locations of active residues targeted by antibodies. (more…)
EGFR Mutant Tyrosine Kinase Mutations in EGFR lead to over-expression of proteins and different types of cancers as cells continually and proliferate. This 3D print of EGFR Tyrosine Kinase visualizes the mutations of key residues that lock the protein’s A-loop (orange) in its active conformation resulting in continued cellular proliferation. (more…)
EGFR Wild Type Tyrosine Kinase This is a 3D print of X-ray crystallography dataset 4HJO, the Crystal Structure of the Inactive EGFR Tyrosine Kinase Domain with Erlotinib. (more…)
Humalog Insulin Hexamer Do you forget to take your medication before meals? Use this 3D printed Biologic Model of Humalog Insulin Hexamer as a desktop reminder to take your medication before each meal. (more…)
CRISPR-Cas13a CRISPR Cas13a is a newly discovered member of the Genome editing system making waves in the biotech community. Explore this 3D printed protein model of CRISPR Cas13a to examine how it uses RNA to target and edit viral RNA. Protein model created from PDB ID: 5XWP (more…)
Cytochrome MtrC 3D Print of Cytochrome MtrC in full-color sandstone. Model created from PDB ID 4LM8 and available in multiple sizes. (more…)
Monoclonal IgG4 Antibody bound to PD1 Humanized antibody are used in cancer immunotherapy to target the programmed cell death receptor (PD-1). Without the PD-1 protective mechanism, the antibody allows the immune system to destroy cancer cells. Explore the 3D structure with our interactive 3D models. (more…)
Oxygenated Hemoglobin Hb Hemoglobin, the protein from inside red blood cells, transports oxygen molecules throughout the body. Its macro-molecular symmetrical structure just the first interesting characteristic of this fascinating molecule. Explore its 3D structure with our 3D printed protein models of Oxygenated Hemoglobin Hb. (more…)
Muscarinic Acetylcholine Receptor 3UON Muscarinic acetylcholine receptors are G protein-coupled receptor complexes in the cell membranes of certain neurons and cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. This 3D printed protein model of muscarinic acetylcholine receptor is visualized by its ribbon structure highlighting the protein’s transmembrane active sites. (more…)
