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Nucleosome 3C1B

Nucleosome, Biologic Models, 3C1B

A Nucleosome is the basic structural unit of DNA that assemble into a chromosome. Each nucleosome consists of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool.  Use this 3D printed model of DNA wrapped around a histone core to explain how DNA is…

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TDP-43 Wild Type and Mutant in Complex with DNA

TDP-43, ALS, Biologic Models

TDP-43 Wild Type and Mutant in Complex with DNA ALS is a fatal motor neuron disorder characterized pathologically by TAR DNA binding protein ( TDP-43 ). The function of TDP-43 is uncertain, and role in ALS remains speculative. Genome scanning reveals mutations associated to neural apoptosis. (more…)

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