High-density lipoprotein (HDL), the carrier of so-called “good” cholesterol, serves as the major athero-protective lipoprotein and has emerged as a key therapeutic target for cardiovascular disease. (more…)
Human cytomegalovirus (HCMV) poses a significant threat to immunocompromised individuals and neonates infected in utero. Glycoprotein B (gB), the herpesvirus fusion protein, is a target for neutralizing antibodies and a vaccine candidate due to its indispensable role in infection. HCMV is the leading infectious cause of congenital abnormalities in the Western world including hearing loss.…
Penicillin acylases (PA) participates in penicillin and cephalosporin biosynthesis. Penicillin acylases (PA) are widely used for the production of semi-synthetic β-lactam antibiotics and chiral compounds. (more…)
CRISPR-Cas13d CRISPR Cas13a is a newly discovered member of the Genome editing system making waves in the biotech community. Explore this 3D printed protein model of CRISPR Cas13a to examine how it uses RNA to target and edit viral RNA. Protein model created from PDB ID: 6IV9 (more…)
CRISPR Cas13d in Complex with crRNA CRISPR Cas13a is a newly discovered member of the Genome editing system making waves in the biotech community. Explore this 3D printed protein model of CRISPR Cas13d (tinted green) to examine how it uses RNA (red) to target and edit viral RNA (purple). Protein model created from PDB ID:…
The SARS-CoV1 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV1 Receptor Binding Domain 5X58 to help research scientists and the general public better understand the binding properties of the Spike Glycoprotein and how it compares to other Coronavirus Spike Glycoproteins.…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 RNA Polymerase is a key target for antiviral therapy. The 3D printed structure of SARS-CoV-2 RNA Polymerase inhibited by Remdesivir should enable the rapid development and evaluation of medical countermeasures to address…
Nucleosome 1KX5 A nucleosome is a basic unit of DNA, consisting of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool. (more…)
CRISPR-Cas13a CRISPR Cas13a is a newly discovered member of the Genome editing system making waves in the biotech community. Explore this 3D printed protein model of CRISPR Cas13a to examine how it uses RNA to target and edit viral RNA. Protein model created from PDB ID: 5XWP (more…)
Cytochrome MtrC 3D Print of Cytochrome MtrC in full-color sandstone. Model created from PDB ID 4LM8 and available in multiple sizes. (more…)
Monoclonal IgG4 Antibody bound to PD1 Humanized antibody are used in cancer immunotherapy to target the programmed cell death receptor (PD-1). Without the PD-1 protective mechanism, the antibody allows the immune system to destroy cancer cells. Explore the 3D structure with our interactive 3D models. (more…)
FAB Antibody bound to Meningococcal fHbp 3D printed protein models of a FAB Antibody bound to Meningococcal fHbp. These models are designed to pair with the academic publication, Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp. (LINK ) (more…)
Shiga Toxin Shiga toxins are a family of related bacterial toxins first discovered by Kiyoshi Shiga while researching the origins of dysentary. Two major groups of this toxin are found in the Shigella dysenteriae and the shigatoxigenic serotypes of Escherichia coli bacteria, Stx1 and Stx2. (more…)
CRISPR-Cpf1 Configure and 3D Print in a variety of materials and sizes a hand-held model of CRISPR Cpf1. This model of Cpf1 can be 3D printed in a variety of materials and sizes. Seen here, Cpf1 is colored blue, DNA colors yellow and green, and guide RNA colored Red. Below is a photo of both our…
T4 Phage bound to Single-Stranded DNA 3D print of T4 Phage bound to single stranded DNA. Multiple materials and sizes available. (more…)
CENP-Histone Bound by Holiday Junction Happy Holidays from Biologic Discovery! 3D Print of a CENP-A-histone H4 complex bound to the Holiday Junction. (more…)
Zinc Fingers bound to DNA 3D print of Zinc Fingers bound to DNA in full-color sandstone. (more…)
Ebolavirus (EBOV) is a highly virulent pathogen capable of causing a severe hemorrhagic fever with 50–90% lethality. The EBOV glycoprotein (GP) is the only virally expressed protein on the virion surface and is critical for attachment to host cells. 3D print model the ectodomain of the Ebolavirus. (more…)
