Proteins can be classified into groups according to structural and functional similarity. These groups often contain well-characterized proteins whose function is known. Thus, when a novel protein is identified, its functional properties can be proposed based on the group to which it is predicted to belong.
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein Intermediate Fusion 6VXX-6XRA to help scientists…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein 7KS9 to help scientists better visualize…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein Postfusion 6XRA to help scientists better…
A nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones. (more…)
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. The 3D printed structure of SARS-CoV-2 Spike Glycoprotein ACE2 Complex 6VXX-6M17 is designed to enable the rapid development and…
Interleukin 8 (IL8 or chemokine ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells, and endothelial cells. (more…)
Negative-strand (NS) RNA viruses initiate infection with a unique polymerase complex. This protein complex mediates both mRNA transcription and subsequent genomic RNA replication. Domains for both functional interactions are contained within a single Large polymerase protein (L-protein). (more…)
T-cell receptors (TCR) are a protein complex found on the surface of T cells that are responsible for identifying fragments of antigen bound to major histocompatibility complex (MHC) molecules. (more…)
High-density lipoprotein (HDL), the carrier of so-called “good” cholesterol, serves as the major athero-protective lipoprotein and has emerged as a key therapeutic target for cardiovascular disease. (more…)
Human cytomegalovirus (HCMV) poses a significant threat to immunocompromised individuals and neonates infected in utero. Glycoprotein B (gB), the herpesvirus fusion protein, is a target for neutralizing antibodies and a vaccine candidate due to its indispensable role in infection. HCMV is the leading infectious cause of congenital abnormalities in the Wwestern world (more…)
Penicillin acylases (PA) participates in penicillin and cephalosporin biosynthesis. Penicillin acylases (PA) are widely used for the production of semi-synthetic β-lactam antibiotics and chiral compounds. (more…)
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 RNA Polymerase is a key target for antiviral therapy. The 3D printed structure of SARS-CoV-2 RNA Polymerase inhibited by Remdesivir should enable the rapid development and evaluation of medical countermeasures to address…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The structural proteins of SARS-CoV-2 are key targets for vaccines, therapeutic antibodies, and diagnostics. The 3D printed structure of SARS-CoV-2 Virion should enable the rapid development and evaluation of medical countermeasures to address…
CRISPR-Cas13d CRISPR Cas13a is a newly discovered member of the Genome editing system making waves in the biotech community. Explore this 3D printed protein model of CRISPR Cas13a to examine how it uses RNA to target and edit viral RNA. Protein model created from PDB ID: 6IV9 (more…)
CRISPR Cas13d in Complex with crRNA CRISPR Cas13a is a newly discovered member of the Genome editing system making waves in the biotech community. Explore this 3D printed protein model of CRISPR Cas13d to examine how it uses RNA to target and edit viral RNA. Protein model created from PDB ID: 6E9F (more…)
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein 6VXX to help scientists better visualize…
Researchers at EMBL in Hamburg recently discovered that the Tuberculosis bacteria has a special toxin-antitoxin system with a surprising function. Once the system activated, all bacterial cells die and stop the disease. (more…)
Cannabinoid receptors are part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory. This 3D print of THC Cannabinoid Receptor Complex 5TGZ is designed to visualize THC bound inside the receptor-binding pocket. (more…)
A Nucleosome is the basic structural unit of DNA that assembles into a chromosome. Each nucleosome consists of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool. Use this 3D printed model Nucleosome 3C1B showing how DNA wraps around a histone core to explain…
Deadly to newborn babies, the Human Respiratory Syncytial Virus (HSV) is a major cause of lower respiratory tract infection. Dynamic structural changes in the Fusion F Glycoprotein reveal and hide binding sites, making targets of new therapies difficult to identify. Explore RSV Fusion F Glycoprotein-3RRR and learn more about its Postfusion 3D structure. (more…)
