Proteins can be classified into groups according to structural and functional similarity. These groups often contain well-characterized proteins whose function is known. Thus, when a novel protein is identified, its functional properties can be proposed based on the group to which it is predicted to belong.
Serotonin receptors are activated by the neurotransmitter like serotonin, which acts as their natural ligand. Other endogenous small molecules, like N-dimethyltryptamine (DMT) and Lysergic acid diethylamide (LSD), competitively bind Serotonin Receptors producing transcendental psychedelic effects. (more…)
Caffeine is a weak, non-selective antagonist of adenosine receptors. This 3D print of Adenosine Receptor (tinted brown) in Complex with Caffeine (colored by atom type) is designed to visualize the location Caffeine (color by atom type) binds to the receptor-binding pocket. (more…)
Cannabinoid receptors are part of the endocannabinoid system, which is involved in a variety of physiological processes including appetite, pain-sensation, mood, and memory. This 3D print of THC Cannabinoid Receptor Complex 5TGZ is designed to visualize THC (color by atom type) bound inside the receptor-binding pocket. (more…)
The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain Delta Plus Mutant 6VXX helps research scientists track viral mutations. (more…)
The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain Delta Plus Mutant 6VXX helps research scientists track viral mutations. (more…)
The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain (RBD) ACE2 Receptor Complex 6M17 to help research scientists and the general public better understand how SARS-CoV-2 binds ACE2 Receptors. (more…)
The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain Neutralizing Antibody Complex 7KS9 to help research scientists and the general public better understand how to neutralize Spike Glycoprotein. (more…)
The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain 6VXX to help research scientists and the general public better understand the binding properties of the Spike Glycoprotein and how it compares to other Coronavirus Spike Glycoproteins.…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The structural proteins of SARS-CoV-2 are key targets for vaccines, therapeutic antibodies, and diagnostics. The 3D printed structure of SARS-CoV-2 Virion should enable the rapid development and evaluation of medical countermeasures to address…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein 7KS9 to help scientists better visualize…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein Postfusion 6XRA to help scientists better…
A nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones. (more…)
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. The 3D printed structure of SARS-CoV-2 Spike Glycoprotein ACE2 Complex 6VXX-6M17 is designed to enable the rapid development and…
The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Spike Glycoprotein 6VXX to help scientists better visualize…
Interleukin 8 (IL8 or chemokine ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells, and endothelial cells. (more…)
Negative-strand (NS) RNA viruses initiate infection with a unique polymerase complex. This protein complex mediates both mRNA transcription and subsequent genomic RNA replication. Domains for both functional interactions are contained within a single Large polymerase protein (L-protein). (more…)
T-cell receptors (TCR) are a protein complex found on the surface of T cells that are responsible for identifying fragments of antigen bound to major histocompatibility complex (MHC) molecules. (more…)
High-density lipoprotein (HDL), the carrier of so-called “good” cholesterol, serves as the major athero-protective lipoprotein and has emerged as a key therapeutic target for cardiovascular disease. (more…)
Human cytomegalovirus (HCMV) poses a significant threat to immunocompromised individuals and neonates infected in utero. Glycoprotein B (gB), the herpesvirus fusion protein, is a target for neutralizing antibodies and a vaccine candidate due to its indispensable role in infection. HCMV is the leading infectious cause of congenital abnormalities in the Wwestern world (more…)
Penicillin acylases (PA) participates in penicillin and cephalosporin biosynthesis. Penicillin acylases (PA) are widely used for the production of semi-synthetic β-lactam antibiotics and chiral compounds. (more…)
