The SARS-CoV-2 Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. Biologic Models designed this 3D printed protein model of the SARS-CoV-2 Receptor Binding Domain Neutralizing Antibody Complex 7KS9 to help research scientists and the general public better understand how to neutralize Spike Glycoprotein.
SARS-CoV-2 Receptor Binding Domain Antibody Complex 7KS9
The Receptor Binding Domain of the SARS-CoV-2 Spike Glycoprotein (PDB ID: 7KS9 seen below) is blocked from binding ACE2 Receptors when Antibodies bind the Receptor Binding Domain’s Binding Motif (dark green). Understanding which residues form bonds between the Spike RBD and Antibody is necessary to predict the potential impact of mutations to alter or evade immune responses.
Biologic Explorer: 7KS9-RBD