Nucleosome, Biologic Models, 3C1B

Nucleosome

Protein Description 3C1B

Here we present crystal structures of nucleosomes reconstituted with methylated histones and investigate the folding behavior of resulting arrays. We demonstrate that dimethylation of histone H3 at lysine residue 79 locally alters the nucleosomal surface, whereas trimethylation of H4 at lysine residue 20 affects the higher-order structure. 

Model Description

This is a 3D printed model of Nucleosome. A nucleosome is a structural unit of a eukaryotic chromosome, consisting of a length of DNA coiled around a core of histones. The core is made up of 8 histone proteins colored purple according to their bFactor, warmest=pink, coolest=blue. The coiled DNA strand is colored from N to C Terminal blue to red. This allows us to see the anti-parallel winding of one DNA strand to another.

3D Print Nucleosome

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CRISPR Cpf1, Biologic Models,

3D Print CRISPR Cpf1

Configure and 3D Print in a variety of materials and sizes a hand-held model of CRISPR Cpf1. This model of Cpf1 can be 3D printed in a variety of materials and sizes. Seen here, Cpf1 is colored blue, DNA colors yellow and green, and guide RNA colored Red. Below is a photo of both our CRISPR Cpf1 and Cas9 models.

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