Biologic Model of DPP4 without Inhibitor 2RGU and 3D printed in full-color sandstone. The protein model of DPP-4 is colored according to the protein’s bFactor. Isolated and colored by atom type is the active binding site in the interior pocket of DPP-4.
A new chemical class of potent DPP-4 inhibitors structurally derived from the xanthine scaffold for the treatment of type 2 diabetes has been discovered and evaluated. Systematic structural variations have led to 1 (BI 1356), a highly potent, selective, long-acting, and orally active DPP-4 inhibitor that shows considerable blood glucose lowering in different animal species. 1 is currently undergoing clinical phase IIb trials and holds the potential for once-daily treatment of type 2 diabetics.
For international customers outside the US, please visit the model on our 3D printing service’s international website: LINK
Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating.
Designed to be used wih DPP4 Small Molecule Inhibitor (2RGU)