DPP4 Small Molecule Inhibitor 2RGU

Biologic Model of DPP4 Small Molecule Inhibitor 2RGU 3D printed in full-color sandstone.

SKU: 1636962795622-dpp4-small-molecule-inhibitor-2rgu Categories: , , Tags: , , , , , ,

Description

Biologic Model of DPP4 Small Molecule Inhibitor 2RGU 3D printed in full-color sandstone. The protein model of DPP-4 is colored according to the protein’s bFactor. Isolated and colored by atom type is the active binding site in the interior pocket of DPP-4.

Protein Description

A new chemical class of potent DPP-4 inhibitors structurally derived from the xanthine scaffold for the treatment of type 2 diabetes has been discovered and evaluated. Systematic structural variations have led to 1 (BI 1356), a highly potent, selective, long-acting, and orally active DPP-4 inhibitor that shows considerable blood glucose lowering in different animal species. 1 is currently undergoing clinical phase IIb trials and holds the potential for once-daily treatment of type 2 diabetics.

For international customers outside the US, please visit the model on our 3D printing service’s international website: LINK

Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating.

Designed to be used with DPP-4 without Inhibitor.