Protein Description

Clustered Regularly Interspaced Short Palindromic Repeats from Prevotella and Francisella CRISPR/Cpf1 is a DNA-editing technology analogous to the CRISPR Cas9 system, characterized in 2015 by Feng Zhang’s group from the Broad Institute and MIT. Cpf1 is an RNA-guided endonuclease of a class II CRISPR/Cas system. This acquired immune mechanism is found in Prevotella and Francisella bacteria. It prevents genetic damage from viruses. Cpf1 genes are associated with the CRISPR locus, coding for an endonuclease that use a guide RNA to find and cleave viral DNA. Cpf1 is a smaller and simpler endonuclease than Cas9, overcoming some of the CRISPR/Cas9 system limitations. CRISPR/Cpf1 could have multiple applications, including treatment of genetic illnesses and degenerative conditions.

CRISPR, Cpf1, Genomics, Biologic Models, Biologic Animation,
Biologic Animation, Biologic Models, CRISPR,Cpf1,
Biologic Animation, Biologic Models, CRISPR, Cpf1
CRISPR, Cpf1, Genome, Molecular Animation, Biologic Animation, Biologic Models,
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Download the free Augmented Reality App

Download the free CRISPR Cpf1 Biologic Explorer App and explore the internal atomic structures of the protein. Launch the Biologic Explorer and point your phone at this QR Code or the nameplate on the CRISPR Cpf1 base to launch a digital model of CRISPR Cpf1. Toggle on and off different structures to reveal the hidden beauty of x-ray crystallography data.


Purchase 3D Print CRISPR Cpf1

Model Description

This is a 3D print of CRISPR Cpf1 created in full-color sandstone. The model depicts CRISPR (blue) bound to its guide RNA (red) while editing its Target DNA (yellow and green). The subtle color variations in the CRISPR are associated with its bFactor, or atomic temperature. The darker the color, the less the protein moves with a cooler atomic temperature. Consider purchasing an Augmented Reality base for your CRISPR Cpf1 protein model.

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