Sphingosine kinase 1 3vzb

3D printed protein model of Sphingosine kinase 1 3vzb printed in full-color sandstone and colored by the protein’s bFactor.

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Sphingosine kinase 1 (SphK1) is a lipid kinase that catalyzes the conversion of sphingosine to sphingosine-1-phosphate (S1P), which has been shown to play a role in lymphocyte trafficking, angiogenesis, and response to apoptotic stimuli. The SphK1 structures reveal a two-domain architecture in which its catalytic site is located in the cleft between the two domains and a hydrophobic lipid-binding pocket is buried in the C-terminal domain.

Model Description

3D printed protein model of Sphingosine kinase 1 printed in full-color sandstone and colored by the protein’s bFactor.

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Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating. Natural finish does not.

Created from PDB ID: 3vzb