Histone H3K27 methylation by PRC2 (Polycomb repressive complex 2) is essential for cellular differentiation and development. This histone interaction is mimicked by PRC2’s cofactor’s JARID2 and zinc finger protein AEBP2.
Biologic Model of PRC2 (multi-colored) in complex with cofactors AEBP2 (red) and JARID2 (magenta) and 3D printed in full color sandstone. Model is colored to match the the visualizations from its publication. PUBMED.
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Created from PDB ID: 6C24