Mus81-Eme1 DNA Complex 4P0R

Biologic Model of Mus81 DNA Complex 3D printed in full-color sandstone visualizing Mus81’s hydrophicity (blue-red) and DNA (Greens).

SKU: 1482115121254-mus81-eme1-dna-complex-4p0r Categories: , Tags: ,

Description

Biologic Model of Mus81 DNA Complex 3D printed in full-color sandstone visualizing Mus81’s hydrophicity (blue-red) and DNA (Greens).

Protein Description

The Mus81-Eme1 endonuclease plays a critical role in during DNA repair. Formation of DNA complex reveals that Mus81-Eme1 undergoes gross substrate-induced conformational changes that reveal two key features: (i) a hydrophobic wedge of Mus81 that separates pre- and post-nick duplex DNA and (ii) a “5′ end binding pocket” that hosts the 5′ nicked end of post-nick DNA.

For international customers outside the US, please visit the model on our 3D printing service’s international website: LINK

Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating. Natural finish does not.

Created from PDB ID 4P0R.