This is a 3D print of PIP4K II Beta created from PDB ID 3xo4. This model is colored by atom type showing blue nitrogen and red oxygen atoms. All other atoms are colored white. These models are printed in full-color sandstone available in multiple sizes
Phosphatidylinositol 4-kinase beta (PI4KB) is an intracellular protein that traffics between the cytoplasm and nucleus. In the cytoplasm, Pi4K can be recruited to the membranes of the Golgi apparatus by GTP binding proteins Arf1 and Rab11. PI4KB is phosphorylated by kinase D. This interaction with stabilizes PI4K in an active conformation and regulates the trafficking from the Golgi system to the plasma membrane. Its nuclear function remains is not yet fully understood, and the study of its structure remains of significance.