SKU: 4928428703846-nemo-6mi3 Category: Tag:


Model Description

Biologic Model of NEMO 6MI3 3D printed in full-color sandstone.

Protein Description

NEMO is an essential component in the activation of the canonical NF-κB pathway and exerts its function by recruiting the IκB kinases (IKK) to the IKK complex. Inhibition of the NEMO/IKKs interaction is an attractive therapeutic paradigm for diseases related to NF-κB mis-regulation, but a difficult endeavor because of the extensive protein-protein interface.