This 3D print is intended to be used with the Ebola Virus Prefusion Ectodomain. There are 3 sizes of the base, one base for each size of the models (Small, Medium, Large). On the bottom of each base is a QRC code that links back to an informational webpage about the model. This 3D printed base is intended to be used with the Ebola Virus Prefusion Ectodomain.
Ebola virions contain a surface transmembrane glycoprotein (GP) that is responsible for binding to target cells and subsequent fusion of the viral and host-cell membranes. GP is expressed as a single-chain precursor that is posttranslationally processed into the disulfide-linked fragments GP1 and GP2. The GP2 subunit is thought to mediate membrane fusion. A soluble fragment of the GP2 ectodomain, lacking the fusion-peptide region and the transmembrane helix, folds into a stable, highly helical structure in aqueous solution. Limited proteolysis studies identify a stable core of the GP2 ectodomain. This 74-residue core, denoted Ebo-74, was crystallized, and its x-ray structure was determined at 1.9-A resolution. Ebo-74 forms a trimer in which a long, central three-stranded coiled coil is surrounded by shorter C-terminal helices that are packed in an antiparallel orientation into hydrophobic grooves on the surface of the coiled-coil.
For international customers outside the US, please visit the model on our 3D printing service’s international website: LINK
Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating.