Ebola Virus Base

This 3D printed base is intended to be used with the Ebola Virus Prefusion Ectodomain.

SKU: 1370814480486-ebola-virus-base Categories: , Tags: , ,

Description

This 3D print is intended to be used with the Ebola Virus Prefusion Ectodomain. There are 3 sizes of the base, one base for each size of the models (Small, Medium, Large). On the bottom of each base is a QRC code that links back to an informational webpage about the model. This 3D printed base is intended to be used with the Ebola Virus Prefusion Ectodomain.

Protein Description

Ebola virions contain a surface transmembrane glycoprotein (GP) that is responsible for binding to target cells and subsequent fusion of the viral and host-cell membranes. GP is expressed as a single-chain precursor that is posttranslationally processed into the disulfide-linked fragments GP1 and GP2. The GP2 subunit is thought to mediate membrane fusion. A soluble fragment of the GP2 ectodomain, lacking the fusion-peptide region and the transmembrane helix, folds into a stable, highly helical structure in aqueous solution. Limited proteolysis studies identify a stable core of the GP2 ectodomain. This 74-residue core, denoted Ebo-74, was crystallized, and its x-ray structure was determined at 1.9-A resolution. Ebo-74 forms a trimer in which a long, central three-stranded coiled coil is surrounded by shorter C-terminal helices that are packed in an antiparallel orientation into hydrophobic grooves on the surface of the coiled-coil.

For international customers outside the US, please visit the model on our 3D printing service’s international¬†website:¬†LINK

Select the desired material finish and size below. Matte finish applies a UV protective, semi-glossy coating.