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3D Print of RsmE bound to the Shine-Dalgarno of mRNA

RsmE, CsrA, 2JPP, Biologic Models

This is a 3D print of RsmE bound to two strands of mRNA visualized as a ribbon bound to nucleotide sequences. The RsmE homodimer is colored blue and purple according to protein’s beta sheet and helices. In red and orange are the two RNA-binding sites. mRNA is colored shades of green according to nucleotide type.…

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3D Print of Tresiba Insulin Hexomer

3D print of Tresiba Insulin Hexomer

This is a model of the pharmaceutical drug Tresiba, insulin degludec, in its stable macro-molecule hexamer form. Tresiba is a fascinating drug, engineered to create long, macromolecular filaments that get stored in fat. Attached to each hexamer are 6 hydrocarbon chains (blue-cyan sticks). They act like tails reaching out to a neighbor hexamer to bind.…

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3D Print of Novolog Insulin Hexomer

3D Print of Novolog Insulin Hexomer

This is a model of the pharmaceutical drug Novolog, insulin aspart, in its stable macro-molecule hexamer form. It is colored by the protein’s bFactor, or atomic temperature. Chains A and C are stained yellow, and Chains B and D are stained dark orange-red. The core of the macromolecule shows the stable, cool binding region of each monomer, an…

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Hemoglobin Gets Its Own Action Figure

Creating a Protein Action Figure Shortly after creating the first 3D print of Oxygenated Hemoglobin, Wired Magazine found our blog post and wanted to write a short article on it. By the time the article was ready for press, Michael Gulen and I had completed our prototype of Oxygenated Hemoglobin cast in durable colored plastics…

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3D Print of Porcine Trypsin

1S81, Porcine Trypsin

Trypsin is a protease enzyme from the digestive system. Trypsin hydrolyzes proteins adding water molecules to specific structures and cuts up other proteins into pieces. Trypsin is used in a variety of biotechnologies to break down proteins, commonly referred to as trypsinization. Protein Description “An understanding of the physiological and toxicological properties of borate and the utilization…

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