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Nucleosome 3C1B

Nucleosome, Biologic Models, 3C1B

Nucleosome 3C1B Nucleosome 3C1B is a basic unit of DNA, consisting of a segment of DNA wound in sequence around eight histone protein cores. This structure is often compared to thread wrapped around a spool.  Use this 3D printed model of DNA wrapped around a histone core to explain how DNA is organized within a chromosome. (more…)

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RSV Fusion F Glycoprotein

RSV, Fusion, Glycoprotein, Prefusion, 3rrr

Deadly to newborn babies, the Human Respiratory Syncytial Virus (HSV) is a major cause of lower respiratory tract infection. Dynamic structural changes in the Fusion F Glycoprotein reveal and hide binding sites, making targets of new therapies difficult to identify. Explore RSV Fusion F Glycoprotein-3RRR and learn more about its Postfusion 3D structure. (more…)

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EGFR Mutant Tyrosine Kinase

EGFR, Mutant, Biologic Models

EGFR Mutant Tyrosine Kinase Mutations in EGFR lead to over-expression of proteins and different types of cancers as cells continually and proliferate. This 3D print of EGFR Tyrosine Kinase visualizes the mutations of key residues that lock the protein’s A-loop (orange) in its active conformation resulting in continued cellular proliferation. (more…)

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Monoclonal IgG4 Antibody bound to PD1

Pembrolizumab, ( KEYTRUDA ), PD1, Keytruda, Biologic Models

Monoclonal IgG4 Antibody bound to PD1 Humanized antibody are used in cancer immunotherapy to target the programmed cell death receptor (PD-1). Without the PD-1 protective mechanism, the antibody allows the immune system to destroy cancer cells. Explore the 3D structure with our interactive 3D models. (more…)

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Oxygenated Hemoglobin Hb

Oxygenated Hemoglobin Hb Hemoglobin, the protein from inside red blood cells, transports oxygen molecules throughout the body. Its macro-molecular symmetrical structure just the first interesting characteristic of this fascinating molecule. Explore its 3D structure with our 3D printed protein models of Oxygenated Hemoglobin Hb. (more…)

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RSV Fusion Glycoprotein

RSV, Fusion, Glycoprotein, Prefusion, 5TDL

This is a 3D print of the RSV Fusion Glycoprotein in its prefusion state. The 3D printed protein models of RSV Fusion F Glycoprotein visualize the conformational changes of this viral protein during membrane fusion. Two chains are colored shades of magenta, with the third chain colored blue to red from N to C-Terminal. (more…)

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FAB Antibody bound to Meningococcal fHbp

fHbp, Fusion H-binding protein, Antibody, FAB, Biologic Models

FAB Antibody bound to Meningococcal fHbp 3D printed protein models of a FAB Antibody bound to Meningococcal fHbp. These models are designed to pair with the academic publication, Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp. (LINK ) (more…)

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Oligosaccharyltransferase Complex

Oligosaccharyltransferase Complex, OST, ETH Zurich, Biologic Models

Oligosaccharyltransferase Complex This is a 3D print of oligosaccharyltransferase (OST) complex. It is colored blue according to the protein’s electrostatic property. Colored green are various monosaccharides attached to OST as sugar trees. Isolated and colored by atom type are the binding residues that attach shuttling proteins. Colored white are individual phospholipids from a plasma membrane.…

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Shiga Toxin

Shiga Toxin Shiga toxins are a family of related bacterial toxins first discovered by Kiyoshi Shiga while researching the origins of dysentary. Two major groups of this toxin are found in the Shigella dysenteriae and the shigatoxigenic serotypes of Escherichia coli bacteria, Stx1 and Stx2. (more…)

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