EGFR Tyrosine Kinase

EGFR, 3W2O, 4HJO, Biologic Models

Conducting comparative analysis of known protein structures to unknown protein structures of allows researchers and scientists to develop theories about protein behavior. Here we investigate the structural differences of inactive EGFR and a mutant EGFR in order to understand the how pharmaceutical products prevent cellular proliferation.

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3D Reconstruction of Human Hemoglobin

Reconstructing Hemoglobin So, about 6 months ago, I got introduced to David Gittleman, over at the McFarlane Design Group. Now, McFarlane Design Group is world famous for making some of the best action figures and toys produced today.  Todd McFarlane, himself a superhero comic book artist, entrepreneur, and author, just had his Amazing Spiderman 313…

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Wired Magazine-Hemoglobin Gets Its Own Action Figure

Shortly after creating the first 3D print of Oxygenated Hemoglobin, Wired Magazine found our blog post and wanted to write a short article on it. By the time the article was ready for press, Michael Gulen and I had completed our prototype of Oxygenated Hemoglobin cast in durable colored plastics from silicon molds. Thanks again…

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MT-3724 Immunotoxin

This 3D print of MT-3724 demonstrates a unique mechanism of action of this immunotoxin. MT-3724 is a new type of immunotherapy developed by Molecular Templates.

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Protein Models as tools for STEM Education

Oxygenated Hemoglobin Hb, Hemglobin, Hb, Haemoglobin, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,

We’ve known college students enjoy using protein models as tools for STEM Education and learn equally well from both computer-aided molecular visualization software as they do physical models. Could the same apply to grade-school children?

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Mechanism of Disease 3D Animation

This is an example of a Mechanism of Disease 3D animation. ‘MOD’ 3D animations are narrative educational videos that explain how normal physiology develops into pathology. Mechanism of Disease 3D Animation  

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Covidien Tristaple Technology

Medical device companies need 3D-animations to explain how their products work in the body. In these narratives, we focus on highlighting technological advancements and marketplace advantages of our clients. This animation showcases our the new Tristaple product line from Covidien demonstrating an increased safety and patient tolerance profile through decrease pressure and tissue damage. Surgical…

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2.5D Medical Animation

This is an example of 2.5D animation. 2D animation that uses 3D animated elements. This is a simpler, faster way to tell some stories and provides clients with greater flexibility when deciding on stylistic approaches.  

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Zaltrap MOA 3D Animation

Depicting dynamic macro-molecular structures is an exciting part of our storytelling process. See some examples of this in our Zaltrap MOA Medical Animation. (more…)

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The Ladders Chairs Spot

This is a commercial done by Method Studios back in 2009. I took care of 3 shots start to finish, including the flocking chair simulation seen in the middle of the commercial.

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The Lifecycle of HIV

Learn about the process we go through to create 3D medical animations about complex and fascinating biochemical processes.

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Insulin Receptor Complex

Insulin Receptor, 3W14, 4ZXB

Insulin is a chemical messenger produced by the pancreas in response to food. Use this 3D printed Biologic Model of the Insulin Receptor Complex as a desktop reminder to take your medication before each meal. This model is generated from PDB IDs:  3Wi4 and 2MFR. It is color coded to denote the dimer configuration on the plasma membrane.

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Ebola Virus Ectodomain

Ebola Virus, Ectodomain, Biologic Models

The crystal structure of the Ebola Virus Glycoprotein in its trimeric, prefusion conformation is derived from a human survivor of the 1995 Kikwit outbreak. In this 3D exploration of the Ebola Virus Glycoprotein, we will investigate different surface properties and binding sites through 3D printed models and animation.

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Oxygenated Hemoglobin Hb

Hemoglobin, Hb, 1HHO, Biologic Models

Sugar attaches to hemoglobin (Hb) and changes the protein’s shape, impairing its function. Learn more about the dangers of high blood sugar and the importance of knowing your HbA1c test scores using 3D reproductions of Glycated Hemoglobin (HbA1c).

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GLP-1 Comparative Analysis

Understanding the relationship of GLP-1 and a natural animal analog to their receptors provides important insights into a rational model for drug design of next-generation GLP-1 analogs. These 3D prints of GLP-1 designed to comparative GLP-1 and its receptor to analogs. The set includes the natural GLP-1 hormone, an natural analog, and synthetic drug.

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