PIP4K II Alpha and Beta
Recently, Cornell University commissioned us to create 3D printed models of PIP4K II Alpha and Beta for the purpose of demonstrating PIP4K dimerization.
This is a 3D print of Shiga Toxin (Stk1) created from protein dataset 1DM0 This model is colored by protein chain. The 5 blue chains are the membrane binding domains and the red the cytotoxic compounds.
This 3D printed protein model of Asparaginase identifies an engineered mutation that extends the protein's half-life. It is printed in full-color sandstone color green to blue by the protein's bFactor. In red is the site of the mutation responsible for prolonging the protein's half-life.
This 3D print of MT-3724 demonstrates a unique mechanism of action of this immunotoxin. MT-3724 is a new type of immunotherapy developed by Molecular Templates.
Comparative Analysis of EGFR
Conducting comparative analysis of known protein structures to unknown protein structures of allows researchers and scientists to develop theories about protein behavior. Here we investigate the structural differences of inactive EGFR and a mutant EGFR in order to understand the how pharmaceutical products prevent cellular proliferation.
GLP-1 Comparative Analysis
Understanding the relationship of GLP-1 and a natural animal analog to their receptors provides important insights into a rational model for drug design of next-generation GLP-1 analogs.