Diabetes

  • PIP4K, Lewis Cantley, Biologic Model

    PIP4K II Alpha and Beta

    Recently, Cornell University commissioned us to create 3D printed models of PIP4K II Alpha and Beta for the purpose of demonstrating PIP4K dimerization.

  • Glycated Hemoglobin, HbA1c, Biologic Models

    Glycated Hemoglobin HbA1c

    3D reproduction of Glycated Hemoglobin HbA1c protein. Glucose and fructose attach to hemoglobin in a process called glycosylation. When sugar attaches to proteins, it changes the protein's shape, impairing its ability to achieve its maximum conformation state and function.
  • Oligosaccharyltransferase Complex, OST, Biologic Models

    Oligosaccharyltransferase Complex

    ETH Zurich researchers make a major breakthrough in our understanding of the glycosylation process after crystallization of the Oligosaccharyltransferase (OST) Complex, the protein that attaches sugar chains. Biologic Models visualizes this dataset as a 3D Printed Protein Model.

  • GLP-1 Comparative Analysis

    Understanding the relationship of GLP-1 and a natural animal analog to their receptors provides important insights into a rational model for drug design of next-generation GLP-1 analogs.

  • Hemoglobin, Hb, 1HHO, Biologic Models

    Oxygenated Hemoglobin Hb

    3D reproduction of Oxygenated Hemoglobin Hb, 18 Million times larger than diameter actual protein. Colored in red are the protein’s HEME Groups, disk-like structures with an Iron atom core. It is to this Iron atom core that binds O2 molecules (Blue) bind.

  • Insulin Receptor, 3W14, 4ZXB

    3D Print of the Insulin Receptor bound by Insulin

    This is a 3D print of the Insulin Receptor in complex with Insulin. This model is generated from PDB IDs:  3Wi4 and 2MFR. It is color coded to denote the dimer configuration on the plasma membrane.