The outbreak of a novel coronavirus (SARS-CoV-2) represents a pandemic threat that has been declared a public health emergency of international concern. The CoV Spike Glycoprotein is a key target for vaccines, therapeutic antibodies, and diagnostics. The structure of SARS-CoV-2 Spike Glycoprotein 6VXX should enable the rapid development and evaluation of medical countermeasures to address…
Deadly to newborn babies, the Human Respiratory Syncytial Virus (HSV) is a major cause of lower respiratory tract infection. Dynamic structural changes in the Fusion F Glycoprotein reveal and hide binding sites, making targets of new therapies difficult to identify. Explore RSV Fusion F Glycoprotein-3RRR and learn more about its Postfusion 3D structure. (more…)
Argonaute Protein Small RNA sequences guide Argonaute Protein (Apo) to its specific DNA targets, which then leads to mRNA cleavage or translation inhibition. Inside the gut, bacteria express control over their host organism by secreting Nitric Oxide which modulates Apo function. Explore the 3D structure of Argonaute Protein. (more…)
The Human Cytomegalovirus (HCMV) is the leading cause of viral birth defects. HCMV Pentamer Complex is considered a key target candidate for vaccine therapies. How HCMV avoids humoral immunity is not clear. New research into the elusive virus reveals the surprising role of the host cell’s endoplasmic reticulum to aid viral infection. (more…)
Zika Virus Shell This is 3D protein model of the Zika Virus Shell 3D printed in full-color sandstone and denotes the locations of active residues targeted by antibodies. (more…)
CRISPR-Cas13a CRISPR Cas13a is a newly discovered member of the Genome editing system making waves in the biotech community. Explore this 3D printed protein model of CRISPR Cas13a to examine how it uses RNA to target and edit viral RNA. Protein model created from PDB ID: 5XWP (more…)
CRISPR-Cas9 Use this 3D printed protein model of CRISPR-Cas9 to explain how bacteria evolved to use viral RNA to guide molecular machinery to combat the invasion of viruses by cutting out viral DNA. (more…)
CRISPR-Cpf1 Configure and 3D Print in a variety of materials and sizes a hand-held model of CRISPR Cpf1. This model of Cpf1 can be 3D printed in a variety of materials and sizes. Seen here, Cpf1 is colored blue, DNA colors yellow and green, and guide RNA colored Red. Below is a photo of both our…
T4 Phage bound to Single-Stranded DNA 3D print of T4 Phage bound to single stranded DNA. Multiple materials and sizes available. (more…)
Ebolavirus (EBOV) is a highly virulent pathogen capable of causing a severe hemorrhagic fever with 50–90% lethality. The EBOV glycoprotein (GP) is the only virally expressed protein on the virion surface and is critical for attachment to host cells. 3D print model the ectodomain of the Ebolavirus. (more…)
