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3D Prints of FAB Antibody bound to Meningococcal fHbp

fHbp, Fusion H-binding protein, Antibody, FAB, Biologic Models

3D printed protein models of a FAB Antibody bound to Meningococcal fHbp. These models are designed to pair with the academic publication, Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp. (LINK ) (more…)

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3D Print of Shiga Toxin

Shiga toxins are a family of related bacterial toxins first discovered by Kiyoshi Shiga while researching the origins of dysentary. Two major groups of this toxin are found in the Shigella dysenteriae and the shigatoxigenic serotypes of Escherichia coli bacteria, Stx1 and Stx2. (more…)

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3D Print of Tresiba Insulin Hexomer

3D print of Tresiba Insulin Hexomer

This is a model of the pharmaceutical drug Tresiba, insulin degludec, in its stable macro-molecule hexamer form. Tresiba is a fascinating drug, engineered to create long, macromolecular filaments that get stored in fat. Attached to each hexamer are 6 hydrocarbon chains (blue-cyan sticks). They act like tails reaching out to a neighbor hexamer to bind.…

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3D Print of Novolog Insulin Hexomer

3D Print of Novolog Insulin Hexomer

This is a model of the pharmaceutical drug Novolog, insulin aspart, in its stable macro-molecule hexamer form. It is colored by the protein’s bFactor, or atomic temperature. Chains A and C are stained yellow, and Chains B and D are stained dark orange-red. The core of the macromolecule shows the stable, cool binding region of each monomer, an…

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3D Print of Human Insulin Hexamer

3D Print of Human Insulin Hexomer

This is a 3D print of human insulin in its stable macro-molecule hexamer form. It is colored by the protein’s bFactor or atomic temperature. Chains A and C are stained yellow, and Chains B and D are stained lite orange. The core of the macromolecule shows the stable, cool binding region of each monomer, an important…

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3D Print of CRISPR Cpf1

Biologic Models, CRISPR, Cpf1

This is a volumetric reconstruction of genome editing system, CRISPR Cpf1. It can be 3D printed in a variety of materials and sizes. Seen here, Cpf1 is colored blue, DNA colors yellow and green, and guide RNA colored Red. Below is a photo of both our CRISPR Cpf1 and Cas9 models. (more…)

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3D Print of Inactive EGFR Tyrosine Kinase

This is a 3D print of X-ray crystallography dataset 4HJO, the Crystal Structure of the Inactive EGFR Tyrosine Kinase Domain with Erlotinib. 4TRP Protein Description Epidermal growth factor receptor (EGFR) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor α (TGFα) (note, a…

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