Pembrolizumab, ( KEYTRUDA ), PD1, Keytruda, Biologic Models

Monoclonal IgG4 Antibody bound to PD1

This is a 3D print Bioloigc Model of a humanized antibody used in cancer immunotherapy. This type of antibody is known as “IgG4,” and works on the surface of white blood cells to block a protective mechanism of cancer. Without this protective mechanism, the antibody allows the immune system to destroy those cancer cells. Specifically, this IgG4 antibody targets the programmed cell death 1 (PD-1) receptor.

(more…)

MT-3724, Biologic Models, Molecular Templates,

MT-3724 Realtime 3D Explorer

MT-3724 Protein Model

This is a theoretical model designed from the information contained in the publication listed below. MT-3724 is a unique immunotoxin assembled from a variety of other protein complexes. As an immunotoxin, MT-3724 packs a mean 1-2 punch, triggering apoptosis and an immune response by conjugating bacterial toxins onto an anti-CD20 FAB-fragment.  Learn more about this protein complex by exploring its 3D-structure.  (more…)