Finding the Origins of Life

Clips from the National Geographic Channel’s TV show, Finding the Origins of Life. Follow along with scientists as they discuss theories on life, evolution, and primordial molecular biology.

 

Muscarinic Acetylcholine Receptor, 3UON

3D Print Muscarinic Acetylcholine Receptor

Muscarinic acetylcholine receptors are G protein-coupled receptor complexes in the cell membranes of certain neurons and cells. They play several roles, including acting as the main end-receptor stimulated by acetylcholine released from postganglionic fibers in the parasympathetic nervous system. This 3D printed protein model of muscarinic acetylcholine receptor is visualized by its ribbon structure highlighting the protein’s transmembrane active sites.

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fHbp, Fusion H-binding protein, Antibody, FAB, Biologic Models

3D Prints of FAB Antibody bound to Meningococcal fHbp

3D printed protein models of a FAB Antibody bound to Meningococcal fHbp. These models are designed to pair with the academic publication, Crystal structure reveals vaccine elicited bactericidal human antibody targeting a conserved epitope on meningococcal fHbp. (LINK )

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Oligosaccharyltransferase Complex, OST, ETH Zurich, Biologic Models

3D Print of Oligosaccharyltransferase Complex

This is a 3D print of oligosaccharyltransferase (OST) complex. It is colored blue according to the protein’s electrostatic property. Colored green are various monosaccharides attached to OST as sugar trees. Isolated and colored by atom type are the binding residues that attach shuttling proteins. Colored white are individual phospholipids from a plasma membrane.

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MT-3724, Biologic Models, Molecular Templates,

MT-3724 Realtime 3D Explorer

MT-3724 Protein Model

This is a theoretical model designed from the information contained in the publication listed below. MT-3724 is a unique immunotoxin assembled from a variety of other protein complexes. As an immunotoxin, MT-3724 packs a mean 1-2 punch, triggering apoptosis and an immune response by conjugating bacterial toxins onto an anti-CD20 FAB-fragment.  Learn more about this protein complex by exploring its 3D-structure.  (more…)