Tag Archives | Molecular Templates

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Shiga Toxin

Shiga toxins are a family of related bacterial toxins first discovered by Kiyoshi Shiga while researching the origins of dysentary. Two major groups of this toxin are found in the Shigella dysenteriae and the shigatoxigenic serotypes of Escherichia coli bacteria, Stx1 and Stx2.   As the name suggests, this little bugger causes pretty bad dysentery in humans. Shiga-like Toxin is made of 6 primary chains, 5 […]

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MT-3724, Molecular Templates, Biologic Models,

MT-3724 3D Macromolecule

MT-3724 is a new to immunotherapy from Molecular Templates, currently under investigation for the treatment of non-Hodgkin’s Lymphoma. This immunotoxin is based on Molecular Templates’ Engineered Toxic Bodies (ETBs) drug delivery platform and harnesses the immunotherapy power of receptor-specific targeting. MT-3724 demonstrates a unique mechanism of action, packing a cytotoxic 1-2-3 cancer killing punch. MT-3724’s Mechanism […]

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