Glycated Hemoglobin HbA1c

3D reproduction of Glycated Hemoglobin HbA1c protein. Glucose and fructose attach to hemoglobin in a process called "glycation" that damages the protein, impairing its function by changing hemoglobin's 3-dimensional structure.

Protein Description

Glycated Hemoglobin (HbA1c) is a derivative compound that results when Hemoglobin (Hb) is exposed to high levels of blood sugar for prolonged periods of time. Sugar is extremely cytotoxic, and readily binds to proteins throughout the body. Protein glycation causes structural changes to occur in the protein, preventing it from achieving ideal 3D configurations

Media Gallery

  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,
  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,
  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,

Protein Location

Hemoglobin the most abundant protein inside red blood cells. But this isn’t the only place we find Hemoglobin throughout nature. Various forms of Hemoglobin can be found through the body performing alternative functions, like oxygen storage.

Protein Structure

Hemoglobin is a relatively large protein, it’s reported resolution is 2.1 Å. It is composed of four protein chains: 2 Alpha chains and 2 Beta chains. Each chain contains a single ring-like HEME Group (red x 4) with an iron atom core.

3D Animation

This simple animation showcases the process of “glycation,” when sugar molecules like glucose and fructose bind to hemoglobin and modulating its function.

Hemoglobin Anatomy

Structure Residues Atoms
Chain α 141 1069 (x 2)
Chain ß 146 1123 (x 2)
HEME Group 1 43 (x 4)
Oxygen 1 2 (x 4)
Glucose 1 12 (x 16)

Diabetes Education

The “A1c” Blood Test

The Glycated Hemoglobin HbA1C blood test, or more commonly known as the “A1c” blood test, is an important test given to nearly every single person with diabetes on the planet and many of those at risk for developing diabetes. It is the universally preferred method of diagnosing the onset of pre-diabetes and the only blood test that does not require overnight fasting. Achieving improved A1C scores is an important milestone in lifestyle intervention programs focused on reversing pre-diabetes.

HbvsHbA1c_5

 

As important as this blood test is, the HbA1C blood test is systemically misunderstood by patients and confused with acute blood sugar readings. The Hemoglobin A1C protein model solves this problem by transforming a misunderstood blood test result into an interactive scientific model that patients of all ages can explore while waiting for physicians to begin an appointment.

Photo Gallery

  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,
  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,
  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,
  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,
  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,
  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,
  • Glycated Hemoglobin HbA1c, Hemglobin, HbA1c, Haemoglobin, Diabetes, Blood Test, Casey Steffen, Biologic Models, Biologic Discovery, Protein model, molecule,

Model Description

This is the interactive 3D model of Glycated Hemoglobin A1c (HbA1c) Teaching Model. This model is based on x-ray crystallography data sets: 1HHO, and 3B75. These models are cast by hand in high quality, durable plastics. Attached to the surface of the Hemoglobin model are detachable sugar molecules, magnetized in order to demonstrate the damaging effects of prolonged exposure to high blood sugar, protein glycation. Model dimensions are 4in x 3cm x 3in.

Purchase Model

Purchase one of our custom made Glycated Hemoglobin HbA1c Teaching Model below. Purchase the Oxygenated Hemoglobin model and use the set to explain the difference between good and bad blood glucose control.

Purchase

$275.00 $250.00 Add to cart