Archive | Molecules

Pembrolizumab, Keytruda, PD1, biologic models,

Comparative Analysis of Pembrolizumab and PD-1 Receptor Binding Properties

Immunotherapy is the treatment of cancer using antibodies that target points of failure in the life cycle of cancer cells. Many of these therapies involve altering monoclonal antibodies to target specific proteins associated with different types of cancer. Understanding the binding properties of these proteins is of utmost importance. Pembrolizumab, an igG4 Monoclonal Antibody Some […]

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HbA1c, Hemoglobin A1c, Biologic Models

Hemoglobin A1c Molecular Model Kit

Hemoglobin A1c Blood Test The Hemoglobin A1c (HbA1c) blood test is given to nearly every single person living with diabetes and anyone at risk of developing diabetes. It is the preferred diagnostic tool used around the world to measure a patient’s long-term self-management of diabetes. Hundreds of millions of people each year will receive this test. Yet, despite […]

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Humalog Insulin Hexamer

Humalog Insulin Hexamer

This is a model of the pharmaceutical drug Humalog, insulin lispro, in its stable macro-molecule hexamer form. It is colored by the protein’s bFactor, or atomic temperature. Chains A and C are stained yellow, and Chains B and D are stained dark orange-red. The core of the macromolecule shows the stable, cool binding region of each monomer, an […]

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sandstone_egfr_inactivet_gloss1

Inactive EGFR Tyrosine Kinase

This is a 3D print of X-ray crystallography dataset 4HJO, the Crystal Structure of the Inactive EGFR Tyrosine Kinase Domain with Erlotinib. 4TRP Protein Description Epidermal growth factor receptor (EGFR) exists on the cell surface and is activated by binding of its specific ligands, including epidermal growth factor and transforming growth factor α (TGFα) (note, a […]

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