CENP-Histone Bound by Holiday Junction

Happy Holidays from Biologic Discovery! 3D Print of a CENP-A-histone H4 complex bound to the Holiday Junction.

Protein Description

The crystal structure of an HJURP-CENP-A-histone H4 complex shows that HJURP binds a CENP-A-H4 heterodimer. The C-terminal ?-sheet domain of Holiday Junction caps the DNA-binding region of the histone heterodimer, preventing it from spontaneous association with DNA

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